Autonomic Nervous System & Divisions of the ANS - Neurotransmitters and Receptors
7 important questions on Autonomic Nervous System & Divisions of the ANS - Neurotransmitters and Receptors
What determines the response of the target cell to ACh or NE?
Why is SANS effects long lasting but PANS effects short lasting, where are 2 reasons
- NE is deactivated slower than ACh becuase they are released into the blood and remain there until destroyed by the liver
- NE is an indirectly acting neurotransmitter, using a second-messenger system
Name the 3 areas on which nicotinic receptors are found on
what is the effect of ACh binding to nicotinic receptors always?
- Motor end plates (therefore somatic targets)
- All ganglionic neurons of both sympathetic and parasympathetic divisions
- The hormone-producing cells of the adrenal medulla
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What is the relationship between muscarinic receptors and effector cells stimulated by postganglionic cholinergic fibers?
What are the 2 effects of ACh binding to muscarinic receptors?
Name the 7 chemicals that act as true neurotransmitters or co-transmitters in non-adrenergic, non-cholinergic (NANC) areas
- ATP
- Substance P
- NO
- CO
- 5-HT (Serotonin)
- CCK
- CGRP
Where is cooperation between PANS and SANS seen best in?
how do PANS and SANS work together to control genitalia
PANS fibers cause vasodilation and are responsible for erection of the penis and clitoris.
SANS fibers cause ejaculation of semen in males and reflex peristalsis in females
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