Cell Injury, Inflammation & Oxidative Stress - Inflammation - Type of inflammation

4 important questions on Cell Injury, Inflammation & Oxidative Stress - Inflammation - Type of inflammation

How long can acute inflammation last?
What induces acute inflammation?

Several days
Tissue trauma, microbial invasion or noxious compounds

How long can Subacute inflammation last?

2-6 weeks

How long can chronic inflammation last?
What is a characteristic of chronic inflammation?
Name 4 causes of chronic inflammation

Months - years
Fibrosis
  1. The agent causing inflammation remains therefore continuous triggering of inflammatory response
  2. Autoimmune disease
  3. Recurrent episodes of acute inflammation
  4. Inflammatory and biochemical inducers causing oxidative stress and mitochondrial dysfunction like free radicals
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Why is tissue remodeling important?
What happens to tissue remodeling during chronic inflammation?

Tissue needs to remodel to remain functional after injury
During chronic inflammation tissue is a constant remodel and repair cycle which can lead to end stage disease as a result of severe function loss

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