Immune-mediated toxicity - Activation of NADPH and MAPK
3 important questions on Immune-mediated toxicity - Activation of NADPH and MAPK
What specific patterns can activate the DAMPs?
- Mitochondrial DNA – CpG repeats
What can activate the MAPK-pathway?
Heel veel routes maar ook:
- Polymorphonuclear neutrophils.
- ROS
The MAPK-pathway; what does it activate?
JNK en p38
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