Tutorial title - Visual pathway

4 important questions on Tutorial title - Visual pathway

List the 9 step visual pathway beginning as light entering the eye to the location of interpretation in the visual cortex

  1. Light
  2. photoreceptor
  3. SN onto bipolar cell
  4. SN onto ganglion cell
  5. through ganglion axons which come together and form the optic nerve, exit at the optic disc
  6. The optic nerves meet at the optic chiasm
  7. continue as the optic tracts
  8. These tracts primarily lead to the lateral geniculate nucleus (LGN) of the thalamus, which serves as the predominant synapse and relay station for visual information
  9. Projection fibers called optic radiations carry the signal to the visual cortex located in the occipital lobe of the cerebral hemispheres for final interpretation

Name the 2 Reflexive visual Pathways which Some visual signals also project into

→ brainstem (specifically the superior colliculus) to activate cranial nerves (Oculomotor, Trochlear, and Abducens) that control the muscles moving your eyes
→ suprachiasmatic nucleus

What is the process of converting light energy into a neural signal within the photoreceptors (rods and cones) of the retina called?

phototransduction
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List the 6 step pathway involved in light transduction reaction

  1. Inside photoreceptors light is absorbed by 11-cis-retinal within the pigment called Rhodopsin.
    1. Light changes 11-cis-retinal to 11-all-trans-retinal
  2. Change triggers g protein “transducin” to activate photodiesterase (PDE)
  3. PDE breaks down cGMP → GMP
    1. as [cGMP] decrease , cGMP-gated cation channels of photoreceptors close in response
    2. reduced influx of NA+ & Ca2+ influx
    3. No depolarisation of photoreceptor cell therefore cell remain hyperpolarised
  4. lack of Ca2+ → no IPSPs neurotransmitters are released into the bipolar cells
    1. bipolar cells are not inhibited from depol
  5. Depol opens voltage-gated Ca2+ channels in bipolar cells
    1. a EPSPs neurotransmitters are released into ganglion cell
  6. Action potentials propagate along the optic nerve

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