Summary: Pharm 1

Read the summary and the most important questions on Pharm 1

• 1 Unit 1

• 1.1 Anticoagulants

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• What triggers collagen release in the mechanism of action of coagulation modifiers?

  Injury or insult to vessel walls triggers collagen release.

• What happens after tissue thromboplastin release?

  Tissue thromboplastin release leads to coagulation activation.

• 1.1.1 Heparins

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• What is Heparin Induced Thrombocytopenia (HIT)?

  Heparin Induced Thrombocytopenia (HIT) can develop days after starting heparin. It can lead to serious conditions such as PE, a stroke, or a heart attack. Symptoms include:
  

  • Skin changes
  • Pain/swelling
  • Breathing difficulties
  • Abdominal pain

• 1.1.3 Direct thrombin Inhibitors

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• What type of medication is Dabigatran etexilate (Pradaxa)?

  Dabigatran etexilate (Pradaxa) is an anticoagulant that acts as a direct thrombin inhibitor.

• 1.1.4 Direct Factor Xa Inhibitors

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• What are the names of the Direct Factor Xa Inhibitors shown?

  • Eliquis (apixaban) tablets
  • Xarelto (rivaroxaban) tablets & oral suspension

• 1.1.5 Antiplatelet

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• What type of toothbrush should be used according to the nursing implications?

  Soft bristle toothbrush

• When should the healthcare provider (HCP) be notified?

  Notify HCP prior to procedures

• What should be reported to the healthcare provider?

  Report symptoms to HCP

• 1.1.6 Thrombolytic Drugs

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• What is the specific thrombolytic drug mentioned?

  Alteplase (tPA)

• 1.2 Dyslipidemia

• What are the four types of drug therapies listed for dyslipidemia?

  • HMG-COA Reductase Inhibitors
  • Bile Acid Sequestrants
  • Fibrates
  • Cholesterol Absorption Inhibitors
  • PCSK9 Inhibitors